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Healthcare Resources To find a medical professional who specializes in genetics, you can ask your doctor for a referral or you can search for one yourself. You can also learn more about genetic consultations from MedlinePlus Genetics.

Research Research. Clinical Research Resources ClinicalTrials. Click on the link to go to ClinicalTrials. Please note: Studies listed on the ClinicalTrials.

We strongly recommend that you talk with a trusted healthcare provider before choosing to participate in any clinical study. Learn More Learn More. The CDC is recognized as the lead federal agency for developing and applying disease prevention and control, environmental health, and health promotion and education activities designed to improve the health of the people of the United States. In-Depth Information Medscape Reference provides information on this topic.

You may need to register to view the medical textbook, but registration is free. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. PubMed is a searchable database of medical literature and lists journal articles that discuss Chronic active Epstein-Barr virus infection.

Click on the link to view a sample search on this topic. Have a question? References References. Characterization and treatment of chronic active Epstein-Barr virus disease: a year experience in the United States. June 2, ; 22 Infectious mononucleosis. Kimura H, Cohen JI. Front Immunol. How I treat T-cell chronic active Epstein-Barr virus disease. Jun 28, ; 26 Sullivan JL. Clinical manifestations and treatment of Epstein-Barr virus infection.

Do you know of a review article? Share this content:. Close Copy Link. You May Be Interested In. How to Find a Disease Specialist. Tips for the Undiagnosed. Most commonly, the lymph nodes of the neck are swollen, but any lymph node may be swollen.

In some people, the only symptom is swollen lymph nodes sometimes mistakenly called "swollen glands". In most infected people, an enlarged spleen causes few if any symptoms, but it may rupture, particularly if injured.

An injured The liver may also enlarge slightly. Sometimes the area around the eyes is swollen. Rashes develop infrequently. However, people with an EBV infection who take the antibiotic ampicillin may be more likely to develop a rash.

Other very rare complications include seizures, nerve damage, behavioral abnormalities, inflammation of the brain encephalitis Encephalitis Encephalitis is inflammation of the brain that occurs when a virus directly infects the brain or when a virus, vaccine, or something else triggers inflammation.

The spinal cord may also be involved How long symptoms last varies. After about 2 weeks, symptoms subside, and most people can resume their usual activities. However, fatigue may persist for several more weeks and, occasionally, for months. The symptoms of infectious mononucleosis also occur in many other viral and bacterial infections.

Therefore, infectious mononucleosis is often unrecognized. However, swollen lymph nodes Swollen Lymph Nodes Lymph nodes are tiny, bean-shaped organs that filter lymph fluid. Usually, a simple blood test known as a heterophile antibody or monospot test is done to confirm the diagnosis. This test can sometimes be negative early in illness in adolescents and adults, and if doctors strongly suspect the infection, they can repeat the test about a week later.

This test is much less reliable and often negative in young children with infectious mononucleosis. An alternative test to confirm the diagnosis is a specific antibody blood test for EBV. Antibodies Antibodies One of the body's lines of defense immune system involves white blood cells leukocytes that travel through the bloodstream and into tissues, searching for and attacking microorganisms and Often, a complete blood count is also done.

Finding many characteristic mononuclear white blood cells atypical lymphocytes may be the first clue that the diagnosis is infectious mononucleosis. People with infectious mononucleosis are encouraged to rest during the first week or two, while symptoms are severe.

After about 2 weeks, they may be more active. However, because of the risk of rupturing the spleen, heavy lifting and contact sports should be avoided for at least 1 month, until doctors confirm by examination or sometimes ultrasonography that the spleen has returned to normal size.

This is because mutations in cells infected with EBV can lead to cancerous changes. EBV-associated cancers are uncommon, particularly outside of Africa and some parts of Southeast Asia.

Most people who have had an EBV infection will not go on to develop one of these cancers. Experts are still trying to identify these specific mutations and why EBV infection seems to cause them. EBV may also play a role in the development of other health conditions, including autoimmune disorders and schizophrenia. EBV has long been thought to be linked to autoimmune disorders, such as lupus. Experts believe that EBV may cause changes in the way some genes are expressed. This altered gene expression could increase your risk of developing an autoimmune disorder.

One recent study found a potential link between EBV and an increased risk of developing lupus, an autoimmune condition.

Still, more research is needed to fully understand the potential link between EBV and autoimmune conditions. A recent study looked at the rates of EBV infection in more people both with and without schizophrenia. The researchers also found that participants with genetic risk factors for schizophrenia as well as elevated antibodies were over eight times more likely to have schizophrenia than the control group. Further research is needed to study any possible link between EBV infection and schizophrenia.

It starts out as a typical EBV infection. But they believe genetic factors or mutations in EBV-infected cells may play a role. EBV infection is very common and is spread by coming into contact with infected bodily fluids. If a teenager or adult is infected, they may experience symptoms like fatigue, swollen lymph nodes, and fever.

In very rare cases, EBV can cause a chronic infection, which can be fatal if left untreated. EBV has also been linked with a variety of conditions, including cancers and autoimmune disorders. Is it possible to contract EBV more than once?



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